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Dissection of reverse gyrase activities: insight into the evolution of a thermostable molecular machine†
Reverse gyrase is a peculiar DNA topoisomerase, specific of thermophilic microorganisms, which induces positive supercoiling into DNA molecules in an ATP-dependent reaction. It is a modular enzyme and comprises an N-terminal helicase-like module fused to a C-terminal topoisomerase IA-like domain. Th...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2504306/ https://ncbi.nlm.nih.gov/pubmed/18614606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn418 |
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