An attenuated variant of Coxsackievirus B3 preferentially induces immunoregulatory T cells in vivo.

BALB/c mice infected with the Woodruff variant of coxsackievirus group B type 3 (CVB3W) develop myocarditis mediated by autoimmune cytolytic T lymphocytes. A variant of CVB3W (designated H3-10A1) which infects the myocardium but induces minimal mortality of myocarditis compared to the parental virus...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Loudon, R P, Moraska, A F, Huber, S A, Schwimmbeck, P, Schultheiss, P
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC250243/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1656071/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.11.5813-5819.1991
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