DnaC Inactivation in Escherichia coli K-12 Induces the SOS Response and Expression of Nucleotide Biosynthesis Genes

BACKGROUND: Initiation of chromosome replication in E. coli requires the DnaA and DnaC proteins and conditionally-lethal dnaA and dnaC mutants are often used to synchronize cell populations. METHODOLOGY/PRINCIPAL FINDINGS: DNA microarrays were used to measure mRNA steady-state levels in initiation-d...

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Main Authors: Løbner-Olesen, Anders, Slominska-Wojewodzka, Monika, Hansen, Flemming G., Marinus, Martin G.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2008
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2500167/
https://ncbi.nlm.nih.gov/pubmed/18714349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002984
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