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Expression and localization of Ski determine cell type–specific TGFβ signaling effects on the cell cycle
Transforming growth factor β (TGFβ) promotes epithelial cell differentiation but induces Schwann cell proliferation. We show that the protooncogene Ski (Sloan-Kettering viral oncogene homologue) is an important regulator of these effects. TGFβ down-regulates Ski in epithelial cells but not in Schwan...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2500137/ https://ncbi.nlm.nih.gov/pubmed/18695043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200710161 |
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