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Limited role of Ca(2+)-activated Cl(-) current in early afterdepolarisations

OBJECTIVES: The proarrhythmic, early afterdepolarisations during phase two of the action potential (phase-2 EADs) are associated with secondary Ca(2+) release from the sarcoplasmic reticulum. This makes it probable that the Ca(2+)-activated Cl(-) current (I(Cl(Ca))) may contribute to phase-2 EADs. A...

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Detalhes bibliográficos
Main Authors: Verkerk, A.O., Tan, H.L., Baartscheer, T., Ravesloot, J.H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2499824/
https://ncbi.nlm.nih.gov/pubmed/25696055
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