Cl(-) current blockade reduces triggered activity based on delayed afterdepolarisations

OBJECTIVES: Increasing evidence suggests that a Ca(2+)-activated Cl(-) current (I(Cl(Ca))) contributes to the transient inward current (I(ti)), the current responsible for proarrhythmic delayed after-depolarisations (DADs). Because the equilibrium potential for Cl(-) ions (E(Cl)) in myocytes is arou...

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Autori principali: Verkerk, A.O., Veldkamp, M.W., van Ginneken, A.C.G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2001
Soggetti:
Review Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2499634/
https://ncbi.nlm.nih.gov/pubmed/25696721
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