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Regulation of Branched-Chain Amino Acid Biosynthesis in Salmonella typhimurium: Isolation of Regulatory Mutants

5′,5′,5′-Trifluoro-dl-leucine inhibited the activity of α-isopropylmalate synthetase (the initial enzyme unique to leucine biosynthesis) as well as the growth of Salmonella typhimurium. Mutants of S. typhimurium resistant to the analogue were isolated and characterized. In most cases, they overprodu...

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Publicado en:J Bacteriol
Autores principales: Calvo, J. M., Freundlich, M., Umbarger, H. E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1969
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249844/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4887507/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.97.3.1272-1282.1969
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