Regulation of Branched-Chain Amino Acid Biosynthesis in Salmonella typhimurium: Isolation of Regulatory Mutants

5′,5′,5′-Trifluoro-dl-leucine inhibited the activity of α-isopropylmalate synthetase (the initial enzyme unique to leucine biosynthesis) as well as the growth of Salmonella typhimurium. Mutants of S. typhimurium resistant to the analogue were isolated and characterized. In most cases, they overprodu...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Calvo, J. M., Freundlich, M., Umbarger, H. E.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1969
Assuntos:	Microbial Physiology and Metabolism
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249844/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4887507/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.97.3.1272-1282.1969
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