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Regulation of Branched-Chain Amino Acid Biosynthesis in Salmonella typhimurium: Isolation of Regulatory Mutants

5′,5′,5′-Trifluoro-dl-leucine inhibited the activity of α-isopropylmalate synthetase (the initial enzyme unique to leucine biosynthesis) as well as the growth of Salmonella typhimurium. Mutants of S. typhimurium resistant to the analogue were isolated and characterized. In most cases, they overprodu...

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Dettagli Bibliografici
Autori principali: Calvo, J. M., Freundlich, M., Umbarger, H. E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1969
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC249844/
https://ncbi.nlm.nih.gov/pubmed/4887507
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