Serologic type conversion of a herpes simplex virus type 1 (HSV-1) to an HSV-2 epitope caused by a single amino acid substitution in glycoprotein C.

A monoclonal antibody to herpes simplex virus type 2 glycoprotein C (gC-2) did not recognize wild-type herpes simplex virus type 1 gC (gC-1) but did recognize a mutant gC-1 molecule. This conversion from a type 1 to a type 2 epitope was shown to be due to a single amino acid substitution in gC-1. IM...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Kimmel, K A, Dolter, K E, Toth, G M, Levine, M, Glorioso, J C
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1990
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249707/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2164613/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.8.4033-4036.1990
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