Resistance of herpes simplex virus type 2 to neomycin maps to the N-terminal portion of glycoprotein C.

Entry of herpes simplex virus (HSV) into cells is believed to be mediated by specific binding of envelope proteins to a cellular receptor. Neomycin specifically blocks this initial step in infection by HSV-1 but not HSV-2. Resistance of HSV-2 to this compound maps to a region of the genome encoding...

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Main Authors: Oyan, A M, Dolter, K E, Langeland, N, Goins, W F, Glorioso, J C, Haarr, L, Crumpacker, C S
Formato: Artigo
Idioma:Inglês
Publicado: 1993
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC237561/
https://ncbi.nlm.nih.gov/pubmed/8386261
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