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Inhibition of Tumor Growth Using Salmonella Expressing Fas Ligand
Intravenous administration of bacteria leads to their accumulation in tumors and to sporadic tumor regression. We therefore explored the hypothesis that Salmonella typhimurium engineered to express the proapoptotic cytokine Fas ligand (FasL) would exhibit enhanced antitumor activity. Immunocompetent...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2496919/ https://ncbi.nlm.nih.gov/pubmed/18664657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djn205 |
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