Defective assembly and intracellular transport of mutant paramyxovirus hemagglutinin-neuraminidase proteins containing altered cytoplasmic domains.

The hemagglutinin-neuraminidase (HN) integral membrane protein of paramyxoviruses is expressed at the cell surface as a tetramer consisting of a pair of disulfide-linked dimers. HN has a large C-terminal ectodomain, a 19-residue uncleaved signal-anchor domain, and a 17-residue N-terminal cytoplasmic...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Parks, G D, Lamb, R A
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1990
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249653/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2164588/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.8.3605-3616.1990
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