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Sequence and functional differences between Schmidt-Ruppin D and Schmidt-Ruppin A strains of pp60v-src.

We show that Schmidt-Ruppin D pp60v-src kinase activity is reduced by a mutation previously shown to be associated with Schmidt-Ruppin A pp60v-src temperature sensitivity and that its reduced transforming activity is associated with a conformational change in the SH3 region. The evolutionary relatio...

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Sonraí Bibleagrafaíochta
Main Authors: Reddy, S, Mazzu, D, Mahan, D, Shalloway, D
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1990
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC249629/
https://ncbi.nlm.nih.gov/pubmed/2161957
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