Sequence and functional differences between Schmidt-Ruppin D and Schmidt-Ruppin A strains of pp60v-src.

We show that Schmidt-Ruppin D pp60v-src kinase activity is reduced by a mutation previously shown to be associated with Schmidt-Ruppin A pp60v-src temperature sensitivity and that its reduced transforming activity is associated with a conformational change in the SH3 region. The evolutionary relatio...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Reddy, S, Mazzu, D, Mahan, D, Shalloway, D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249629/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2161957/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.7.3545-3550.1990
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