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Generation of seal influenza virus variants pathogenic for chickens, because of hemagglutinin cleavage site changes.

Influenza virus A/seal/Mass/1/80 (H7N7) was adapted to grow in MDCK cells and chicken embryo cells (CEC) in the absence of exogenous protease. The biological properties of the virus variants obtained coincided with intracellular activation of the hemagglutinin (HA) by posttranslational proteolytic c...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Li, S Q, Orlich, M, Rott, R
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1990
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249560/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2191148/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.7.3297-3303.1990
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