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The Planetary Biology of Ascorbate and Uric acid and their Relationship with the Epidemic of Obesity and Cardiovascular Disease

Humans have relatively low plasma ascorbate levels and high serum uric acid levels compared to most mammals due to the presence of genetic mutations in L-gulonolactone oxidase and uricase, respectively. We review the major hypotheses for why these mutations may have occurred. In particular, we sugge...

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Bibliografiske detaljer
Main Authors: Johnson, Richard J., Gaucher, Eric A., Sautin, Yuri Y., Henderson, George N., Angerhofer, Alex J., Benner, Steven A.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2495042/
https://ncbi.nlm.nih.gov/pubmed/18331782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mehy.2008.01.017
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