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The Planetary Biology of Ascorbate and Uric acid and their Relationship with the Epidemic of Obesity and Cardiovascular Disease

Humans have relatively low plasma ascorbate levels and high serum uric acid levels compared to most mammals due to the presence of genetic mutations in L-gulonolactone oxidase and uricase, respectively. We review the major hypotheses for why these mutations may have occurred. In particular, we sugge...

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書誌詳細
主要な著者: Johnson, Richard J., Gaucher, Eric A., Sautin, Yuri Y., Henderson, George N., Angerhofer, Alex J., Benner, Steven A.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2495042/
https://ncbi.nlm.nih.gov/pubmed/18331782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mehy.2008.01.017
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