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CXCR4 antagonism increases T cell trafficking in the central nervous system and improves survival from West Nile virus encephalitis
The migration of lymphocytes into the CNS during viral encephalitis is hindered by the blood–brain barrier (BBB) such that most infiltrating cells remain localized to perivascular spaces. This sequestration of leukocytes away from the parenchyma is believed to protect the CNS from immunopathologic i...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2495012/ https://ncbi.nlm.nih.gov/pubmed/18678898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800898105 |
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