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TNF-α-dependent regulation of CXCR3 expression modulates neuronal survival during West Nile virus encephalitis
The chemokine CXCL10 exerts antiviral effects within the central nervous system (CNS) through the recruitment of virus-specific T cells. However, elevated levels of CXCL10 may induce neuronal apoptosis given its receptor, CXCR3, is expressed by neurons. Using a murine model of West Nile virus (WNV)...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2910216/ https://ncbi.nlm.nih.gov/pubmed/20579746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2010.05.003 |
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