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Modulation of the mitotic regulatory network by APC-dependent destruction of the Cdh1 inhibitor Acm1
The anaphase-promoting complex (APC) is a ubiquitin ligase that governs late mitotic events by triggering the destruction of mitotic regulatory proteins. The APC is initially activated in early mitosis by association with the activator Cdc20, which is replaced in late mitosis by Cdh1. Here we show t...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2494983/ https://ncbi.nlm.nih.gov/pubmed/18498748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.04.004 |
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