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Crystallization of Spätzle, a cystine-knot protein involved in embryonic development and innate immunity in Drosophila melanogaster

The Spätzle protein is involved in both the definition of the dorsal–ventral axis during embryonic development and in the adult innate immune response. The disulfide-linked dimeric cystine-knot protein has been expressed as a proprotein in inclusion bodies in Escherichia coli and refolded in vitro b...

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Hlavní autoři: Hoffmann, Anita, Neumann, Piotr, Schierhorn, Angelika, Stubbs, Milton T.
Médium: Artigo
Jazyk:Inglês
Vydáno: International Union of Crystallography 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494967/
https://ncbi.nlm.nih.gov/pubmed/18678937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108018812
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