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Expression, purification and crystallization of Helicobacter pylori l-asparaginase

The l-asparaginases from Escherichia coli and Erwinia chrysanthemi are effective drugs that have been used in the treatment of acute childhood lymphoblastic leukaemia for over 30 years. However, despite their therapeutic potential, they can cause serious side effects as a consequence of their intrin...

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Detalhes bibliográficos
Main Authors: Dhavala, Prathusha, Krasotkina, Julya, Dubreuil, Christine, Papageorgiou, Anastassios C.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494961/
https://ncbi.nlm.nih.gov/pubmed/18678946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108020186
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