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Nbs1 dependent binding of Mre11 to Adenovirus E4 mutant viral DNA is important for inhibiting DNA replication
Adenovirus (Ad) infections stimulate the activation of cellular DNA damage response and repair pathways. Ad early regulatory proteins prevent activation of DNA damage responses by targeting the MRN complex, composed of the Mre11, Rad50 and Nbs1 proteins, for relocalization and degradation. In the ab...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2494955/ https://ncbi.nlm.nih.gov/pubmed/18234271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.12.034 |
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