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Discrete state model and accurate estimation of loop entropy of RNA secondary structures

Conformational entropy makes important contribution to the stability and folding of RNA molecule, but it is challenging to either measure or compute conformational entropy associated with long loops. We develop optimized discrete k-state models of RNA backbone based on known RNA structures for compu...

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Autori principali: Zhang, Jian, Lin, Ming, Chen, Rong, Wang, Wei, Liang, Jie
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494904/
https://ncbi.nlm.nih.gov/pubmed/18376982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.2895050
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