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Chronic diet-induced hyperhomocysteinemia impairs eNOS regulation in mouse mesenteric arteries

Hyperhomocysteinemia (HHcy) impairs endothelium-dependent vasodilation by increasing reactive oxygen species, thereby reducing nitric oxide (NO·) bioavailability. It is unclear whether reduced expression or function of the enzyme that produces NO·, endothelial nitric oxide synthase (eNOS), also cont...

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Detalhes bibliográficos
Main Authors: Looft-Wilson, Robin C., Ashley, Blair S., Billig, Janelle E., Wolfert, Madeline R., Ambrecht, Lindsay A., Bearden, Shawn E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494800/
https://ncbi.nlm.nih.gov/pubmed/18448615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00833.2007
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