Suppression of detrusor-sphincter dysynergia by GABA-receptor activation in the lumbosacral spinal cord in spinal cord-injured rats

We investigated the effects of intrathecal application of GABA(A)- or GABA(B)-receptor agonists on detrusor-sphincter dyssynergia (DSD) in spinal cord transection (SCT) rats. Adult female Sprague-Dawley rats were used. At 4 wk after Th(9-10) SCT, simultaneous recordings of intravesical pressure and...

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Autores principales: Miyazato, Minoru, Sasatomi, Kurumi, Hiragata, Shiro, Sugaya, Kimio, Chancellor, Michael B., de Groat, William C., Yoshimura, Naoki
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2008
Materias:
Comparative and Evolutionary Physiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494799/
https://ncbi.nlm.nih.gov/pubmed/18495826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.90315.2008
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