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Endothelin type A receptor antagonist normalizes blood pressure in rats exposed to eucapnic intermittent hypoxia

We have reported that eucapnic intermittent hypoxia (E-IH) causes systemic hypertension, elevates plasma endothelin 1 (ET-1) levels, and augments vascular reactivity to ET-1 and that a nonspecific ET-1 receptor antagonist acutely lowers blood pressure in E-IH-exposed rats. However, the effect of chr...

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Detalhes bibliográficos
Main Authors: Allahdadi, Kyan J., Cherng, Tom W., Pai, Hemanth, Silva, Ana Q., Walker, Benjimen R., Nelin, Leif D., Kanagy, Nancy L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494757/
https://ncbi.nlm.nih.gov/pubmed/18515645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.91477.2007
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