A DNA replication-positive mutant of simian virus 40 that is defective for transformation and the production of infectious virions.

Simian virus 40 (SV40) mutant 5002 carries base pair substitutions of C-5109----T and C-5082----T. These mutations lie in a region of the genome that encodes amino acids common to the large and small viral tumor antigens (T and t antigens, respectively) and result in amino acid substitutions of Leu-...

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Bibliographische Detailangaben
Hauptverfasser: Peden, K W, Spence, S L, Tack, L C, Cartwright, C A, Srinivasan, A, Pipas, J M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1990
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC249475/
https://ncbi.nlm.nih.gov/pubmed/2159552
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