A DNA replication-positive mutant of simian virus 40 that is defective for transformation and the production of infectious virions.

Simian virus 40 (SV40) mutant 5002 carries base pair substitutions of C-5109----T and C-5082----T. These mutations lie in a region of the genome that encodes amino acids common to the large and small viral tumor antigens (T and t antigens, respectively) and result in amino acid substitutions of Leu-...

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Pubblicato in:	J Virol
Autori principali:	Peden, K W, Spence, S L, Tack, L C, Cartwright, C A, Srinivasan, A, Pipas, J M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249475/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2159552/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.6.2912-2921.1990
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