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Human gastrin-releasing peptide receptor gene regulation requires transcription factor binding at two distinct CRE sites
Ectopic expression of the gastrin-releasing peptide (GRP) receptor (GRP-R) occurs frequently in human malignancies of the gastrointestinal tract. Owing to paracrine and autocrine interaction with its specific high-affinity ligand GRP, tumor cell proliferation, migration, and invasion might ensue. He...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Physiological Society
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2494719/ https://ncbi.nlm.nih.gov/pubmed/18483184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00036.2008 |
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