Hepadnavirus envelope proteins regulate covalently closed circular DNA amplification.

Primary duck hepatocytes were infected with a mutant duck hepatitis B virus defective in envelope protein but competent for viral DNA synthesis. Cells infected by this mutant accumulated higher levels of viral covalently closed, circular DNA (cccDNA) than those infected by wild-type virus. The accum...

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Pubblicato in:	J Virol
Autori principali:	Summers, J, Smith, P M, Horwich, A L
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249463/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2335817/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.6.2819-2824.1990
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