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Hepadnavirus envelope proteins regulate covalently closed circular DNA amplification.

Primary duck hepatocytes were infected with a mutant duck hepatitis B virus defective in envelope protein but competent for viral DNA synthesis. Cells infected by this mutant accumulated higher levels of viral covalently closed, circular DNA (cccDNA) than those infected by wild-type virus. The accum...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Summers, J, Smith, P M, Horwich, A L
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1990
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249463/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2335817/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.6.2819-2824.1990
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