Lhx2 selector activity specifies cortical identity and suppresses hippocampal organizer fate

The earliest step in creating the cerebral cortex is the specification of neuroepithelium to a cortical fate. Using mouse genetic mosaics and timed inactivations, we demonstrate that Lhx2 acts as a classic selector gene and essential intrinsic determinant of cortical identity. Lhx2 selector activity...

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Autores principales: Mangale, Vishakha S., Hirokawa, Karla E., Satyaki, Prasad R. V., Gokulchandran, Nandini, Chickbire, Satyadeep, Subramanian, Lakshmi, Shetty, Ashwin S., Martynoga, Ben, Paul, Jolly, Mai, Mark V., Li, Yuqing, Flanagan, Lisa A., Tole, Shubha, Monuki, Edwin S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494603/
https://ncbi.nlm.nih.gov/pubmed/18202285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1151695
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