Transcription factor Lhx2 is necessary and sufficient to suppress astrogliogenesis and promote neurogenesis in the developing hippocampus

The sequential production of neurons and astrocytes from neuroepithelial precursors is a fundamental feature of central nervous system development. We report that LIM-homeodomain (LIM-HD) transcription factor Lhx2 regulates this transition in the developing hippocampus. Disrupting Lhx2 function in t...

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Detalhes bibliográficos
Main Authors: Subramanian, Lakshmi, Sarkar, Anindita, Shetty, Ashwin S., Muralidharan, Bhavana, Padmanabhan, Hari, Piper, Michael, Monuki, Edwin S., Bach, Ingolf, Gronostajski, Richard M., Richards, Linda J., Tole, Shubha
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131330/
https://ncbi.nlm.nih.gov/pubmed/21690374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1101109108
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