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The adenovirus L4 100-kilodalton protein is necessary for efficient translation of viral late mRNA species.

When screening a number of adenovirus type 5 (Ad5) temperature-sensitive mutants for defects in viral gene expression, we observed that H5ts1-infected 293 cells accumulated reduced levels of newly synthesized viral late proteins. Pulse-labeling and pulse-chase experiments were used to establish that...

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Detalles Bibliográficos
Main Authors: Hayes, B W, Telling, G C, Myat, M M, Williams, J F, Flint, S J
Formato: Artigo
Idioma:Inglês
Publicado: 1990
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC249453/
https://ncbi.nlm.nih.gov/pubmed/2335816
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