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The adenovirus L4 100-kilodalton protein is necessary for efficient translation of viral late mRNA species.

When screening a number of adenovirus type 5 (Ad5) temperature-sensitive mutants for defects in viral gene expression, we observed that H5ts1-infected 293 cells accumulated reduced levels of newly synthesized viral late proteins. Pulse-labeling and pulse-chase experiments were used to establish that...

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Foilsithe in:J Virol
Main Authors: Hayes, B W, Telling, G C, Myat, M M, Williams, J F, Flint, S J
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology (ASM) 1990
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249453/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2335816/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.6.2732-2742.1990
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