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Indoleamine 2,3-dioxygenase expression promotes renal ischemia-reperfusion injury
Indoleamine 2,3-dioxygenase (IDO) catabolizes tryptophan to N-formyl kynurenine and has a proapoptotic role in renal tubular epithelial cells (TEC) in response to IFN-γ and TNF-α in vitro. TEC produce abundant amounts of IDO in vitro in response to inflammation but a pathological role for IDO in ren...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Physiological Society
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2494522/ https://ncbi.nlm.nih.gov/pubmed/18480171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00567.2007 |
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