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Nephrin binds to the COOH terminus of a large-conductance Ca(2+)-activated K(+) channel isoform and regulates its expression on the cell surface
We carried out a yeast two-hybrid screen to identify proteins that interact with large-conductance Ca(2+)-activated K(+) (BK(Ca)) channels encoded by the Slo1 gene. Nephrin, an essential adhesion and scaffolding molecule expressed in podocytes, emerged in this screen. The Slo1-nephrin interaction wa...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Physiological Society
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2494500/ https://ncbi.nlm.nih.gov/pubmed/18480178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00140.2008 |
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