Activation of the E2F transcription factor in adenovirus-infected cells involves E1A-dependent stimulation of DNA-binding activity and induction of cooperative binding mediated by an E4 gene product.

Previous experiments have demonstrated that the DNA-binding activity of the E2F transcription factor is increased upon adenovirus infection and that both the E1A and E4 genes are required for activation. In this study, we demonstrated that this enhanced binding of E2F to the E2 promoter is the resul...

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Bibliographic Details
Published in:J Virol
Main Authors: Raychaudhuri, P, Bagchi, S, Neill, S D, Nevins, J R
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1990
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249449/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2139893/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.6.2702-2710.1990
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