Adenovirus E4-dependent activation of the early E2 promoter is insufficient to promote the early-to-late-phase transition.

The adenovirus E4 ORF6/7 protein has been shown to activate the cellular transcription factor E2F. E2F activation leads to activation of the adenovirus early E2 promoter which controls the production of viral DNA replication proteins. In the present study an adenovirus type 5 cDNA mutant, H5ilE4L, w...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Hemström, C, Virtanen, A, Bridge, E, Ketner, G, Pettersson, U
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC239924/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1825341/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.3.1440-1449.1991
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