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Adenovirus E4-dependent activation of the early E2 promoter is insufficient to promote the early-to-late-phase transition.

The adenovirus E4 ORF6/7 protein has been shown to activate the cellular transcription factor E2F. E2F activation leads to activation of the adenovirus early E2 promoter which controls the production of viral DNA replication proteins. In the present study an adenovirus type 5 cDNA mutant, H5ilE4L, w...

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Bibliographic Details
Published in:J Virol
Main Authors: Hemström, C, Virtanen, A, Bridge, E, Ketner, G, Pettersson, U
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1991
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC239924/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1825341/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.3.1440-1449.1991
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