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Insulin-like stimulation of cardiac fuel metabolism by physiological levels of glucagon: involvement of PI3K but not cAMP
At concentrations around 10(−9) M or higher, glucagon increases cardiac contractility by activating adenylate cyclase/cyclic adenosine monophosphate (AC/cAMP). However, blood levels in vivo, in rats or humans, rarely exceed 10(−10) M. We investigated whether physiological concentrations of glucagon,...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2493598/ https://ncbi.nlm.nih.gov/pubmed/18492769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.90228.2008 |
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