Acquired obesity and poor physical fitness impair expression of genes of mitochondrial oxidative phosphorylation in monozygotic twins discordant for obesity

Defects in expression of genes of oxidative phosphorylation in mitochondria have been suggested to be a key pathophysiological feature in familial insulin resistance. We examined whether such defects can arise from lifestyle-related factors alone. Fourteen obesity-discordant (BMI difference 5.2 ± 1....

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Main Authors: Mustelin, Linda, Pietiläinen, Kirsi H., Rissanen, Aila, Sovijärvi, Anssi R., Piirilä, Päivi, Naukkarinen, Jussi, Peltonen, Leena, Kaprio, Jaakko, Yki-Järvinen, Hannele
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493587/
https://ncbi.nlm.nih.gov/pubmed/18460597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00580.2007
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