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Antiproliferative effect of sulindac in colonic neoplasia prevention: role of COOH-terminal Src kinase

Although the nonsteroidal anti-inflammatory drugs (NSAID) protection against colorectal cancer is well established, the molecular mechanisms remain unclear. We show herein that induction of the tumor suppressor gene COOH-terminal Src kinase (Csk) by NSAID is important for their antiproliferative and...

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Detalhes bibliográficos
Main Authors: Kunte, Dhananjay P., Wali, Ramesh K., Koetsier, Jennifer L., Roy, Hemant K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493571/
https://ncbi.nlm.nih.gov/pubmed/18644992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-0022
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