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Autonomous Maturation of α/β T Lineage Cells in the Absence of Cooh-Terminal Src Kinase (Csk)

The deletion of COOH-terminal Src kinase (Csk), a negative regulator of Src family protein tyrosine kinases (PTKs), in immature thymocytes results in the development of α/β T lineage cells in T cell receptor (TCR) β-deficient or recombination activating gene (rag)-1–deficient mice. The function of C...

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Autors principals: Schmedt, Christian, Tarakhovsky, Alexander
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193374/
https://ncbi.nlm.nih.gov/pubmed/11283154
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