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The class V myosin motor, myosin 5c, localizes to mature secretory vesicles and facilitates exocytosis in lacrimal acini

We investigated the role of the actin-based myosin motor, myosin 5c (Myo5c) in vesicle transport in exocrine secretion. Lacrimal gland acinar cells (LGAC) are the major source for the regulated secretion of proteins from the lacrimal gland into the tear film. Confocal fluorescence and immunogold ele...

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Bibliographic Details
Main Authors: Marchelletta, Ronald R., Jacobs, Damon T., Schechter, Joel E., Cheney, Richard E., Hamm-Alvarez, Sarah F.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493552/
https://ncbi.nlm.nih.gov/pubmed/18434623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00330.2007
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