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Minute dosages of α(ν)β(3)-targeted fumagillin nanoparticles impair Vx-2 tumor angiogenesis and development in rabbits
Fumagillin suppresses angiogenesis in cancer models and clinical trials, but it is associated with neurotoxicity at systemic doses. In this study, α(ν)β(3)-targeted fumagillin nanoparticles were used to suppress the neovasculature and inhibit Vx-2 adenocarcinoma development using minute drug doses....
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Federation of American Societies for Experimental Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2493462/ https://ncbi.nlm.nih.gov/pubmed/18362202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.07-103929 |
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