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DXZ4 chromatin adopts an opposing conformation to that of the surrounding chromosome and acquires a novel inactive X-specific role involving CTCF and antisense transcripts
Macrosatellite DNA is composed of large repeat units, arranged in tandem over hundreds of kilobases. The macrosatellite repeat DXZ4, localized at Xq23-24, consists of 50–100 copies of a CpG-rich 3-kb monomer. Here I report that on the active X chromosome (Xa), DXZ4 is organized into constitutive het...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2493436/ https://ncbi.nlm.nih.gov/pubmed/18456864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.075713.107 |
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