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General Anesthetics Have Additive Actions on Three Ligand-Gated Ion Channels

BACKGROUND: The purpose of this study was to determine whether pairs of compounds, including general anesthetics, could simultaneously modulate receptor function in a synergistic manner, thus demonstrating the existence of multiple intra-protein anesthetic binding sites. METHODS: Using standard elec...

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Autores principales: Jenkins, Andrew, Lobo, Ingrid A., Gong, Diane, Trudell, James R., Solt, Ken, Harris, R. Adron, Eger, Edmond I
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493416/
https://ncbi.nlm.nih.gov/pubmed/18633027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ane.0b013e31817b70c1
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