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Structure and function in rhodopsin: Topology of the C-terminal polypeptide chain in relation to the cytoplasmic loops

Cysteine mutagenesis and site-directed spin labeling in the C-terminal region of rhodopsin have been used to probe the local structure and proximity of that region to the cytoplasmic loops. Each of the native amino acids in the sequence T335–T340 was replaced with Cys, one at a time. The sulfhydryl...

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Detalhes bibliográficos
Main Authors: Cai, Kewen, Langen, Ralf, Hubbell, Wayne L., Khorana, H. Gobind
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC24934/
https://ncbi.nlm.nih.gov/pubmed/9405601
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